Positive initial data from study of novel 5-MeO-DMT (DMT) for treatment-resistant depression

TL;DR:

• A single dose of DMT produced a fast antidepressant response in 55% of patients the day after dosing.

• A durable antidepressant effect was also shown, with 55% of patients in remission from depression at day 29 and 45% in remission at day 85.

• DMT demonstrated a short treatment duration, with acute effects resolving and patients deemed dischargeable within an average time of less than 2 hours.

• DMT was generally well-tolerated with no serious adverse events reported.